Cell Migration
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Cell Migration in Development, Health and Disease
Author: Anke Brüning-Richardson
language: en
Publisher: Springer Nature
Release Date: 2024-11-12
This textbook gives an insight into the importance of cell migration in health during development, wound healing and immune responses as well as in disease with particular focus on cancer. The reader will learn about the different ways cells migrate to allow cellular changes during development to occur, as well as responses to injury and threat by foreign invaders. Cell migration is a driver of invasion and ultimately metastasis in cancer and as such we will give examples from highly aggressive cancer such as brain tumours. The book also includes an introduction to mathematical modelling to predict cell migration, information on the development of software for analysis of data generated in 2D and 3D as well as recent developments in the investigations into cell migration using 3D bioprinting. This textbook will be a great learning tool for advanced undergraduate students and Master students with the relevant science degrees such as in cell biology, developmental biology, cancer research, and tumour biology.
Cell Migration in Development
Cell Migration in Development, Volume 163 highlights new advances in the field, with chapters written by an international board of authors who update on high-profile topics such as. Single-cell migration in development - lessons from germ-cells, Lipid/membrane regulation during cell migration and invasion, Remodeling of the extracellular matrix and cell-matrix adhesion during collective cell migration, From cessation of neural crest migration to onset of gangliogenesis, Collective migration in confined spaces: the case of trunk neural crest, From single to collective: the mechanisms underlying cell migration in early development, Direct and indirect roles of Nodal signaling in developmental cell migration. - Provides the latest information on different disciplines, including Cell Biology, Developmental Biology, Genetics, and Molecular biology - Covers reviews on cellular mechanism underlying cell migration in development, exploring signaling pathways and adhesion molecules - Covers lates experimental techniques and imaging approaches, including live cell imaging, genetic manipulation, and advanced microscopy techniques
Cell Migration in Three Dimensions
This detailed collection serves as a unique and excellent collection of state-of-the-art methods and protocols to interrogate cell migration in a wide variety of different contexts and model organisms, as well as advanced image analysis and quantitative assessment of a diverse array of parameters related to cell migration. The book focuses on the cell biology of cell migration, developmental model systems to assess cell migration during morphogenesis, cell migration in cancers and the tumor micro-environment, as well as blood vessel formation and interactions. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cell Migration in Three Dimensions provides a solid foundation for scientists of different disciplines to investigate cell migration in biological processes. Chapters 7, 12, 16, 17, 19, 22, and 24 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.