The Antagonist Program
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The Antagonist Program
Sejak awal Galen Devabrata dan Mari Sahir adalah pemeran utama dalam program Sang Ratu Pilihan. Orang-orang meyakini keduanya sebagai sang protagonis dalam reality show tersebut. Namun, kehadiran Elora Pratista sebagai tokoh antagonis telah berhasil mengacaukan hati dan pikiran Galen. Selama empat bulan penuh ketiganya diwajibkan menghabiskan waktu bersama. Lalu, siapakah yang akan Galen pilih? Sang protagonis baik hati yang merupakan teman masa kecilnya, atau sang antagonis berhati batu yang menyimpan banyak sekali rahasia? "Tahu nggak kenapa tokoh antagonis itu susah matinya?" "Kenapa memang?" "Karena dia punya tugas untuk membuat tokoh-tokoh lain menderita. Dia nggak akan mati sebelum tugasnya terlaksana."
Advances in the Treatment of Sexual Precocity and Infertility
Author: Dimitrios T. Papadimitriou
language: en
Publisher: Frontiers Media SA
Release Date: 2024-12-02
Pediatric - adolescent endocrinology and gynecology are entering a new era. Whole exome sequencing approaches with targeted gene panels have become widely available even for prenatal screening, leading to the elucidation of genetic etiologies in endocrine and gynecological diseases and opening the road for genetic precision medicine and the development of specific therapies. The transition from the end of puberty to the attainment of an adult phenotype may be a very long way - up to 10 years or even longer. Meanwhile, conventional approaches to hormone deficiencies are rapidly changing, as are the options for treatment of sexual precocity and infertility. Commercially available rLH/rFSH preparations in the form of pens - used mainly for fertility induction in women – are now being investigated in hypogonadotropic hypogonadism, aiming to a physiological replacement therapy not only at puberty, but also to the replacement of the missing mini-puberty - crucially important for fertility and the very essence of the male-sex identity itself. Furthermore, they provide an alternative to surgery especially for bilateral cryptorchidism, preserving future fertility.